Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 4/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696043 | 1.00 | HCRTR2 (0.33) | HCRTR2HCRTR1L3MBTL1CA2 | |
| SCHEMBL9695845 | 1.00 | HCRTR2 (0.33) | HCRTR2HCRTR1L3MBTL1CA2 | |
| SCHEMBL9696056 | 0.85 | L3MBTL1 (0.35) | HCRTR2HCRTR1L3MBTL1CA2 | |
| SCHEMBL9694546 | 0.85 | L3MBTL1 (0.35) | HCRTR2HCRTR1L3MBTL1CA2 | |
| SCHEMBL9695839 | 0.76 | CA2 (0.33) | CA2 | |
| SCHEMBL9696049 | 0.76 | CA2 (0.33) | CA2 | |
| SCHEMBL14793073 | 0.74 | MMP9 (0.32) | HCRTR2HCRTR1 | |
| SCHEMBL14790181 | 0.74 | MMP9 (0.32) | HCRTR2HCRTR1 | |
| SCHEMBL14790179 | 0.74 | MMP9 (0.32) | HCRTR2HCRTR1 | |
| SCHEMBL28595773 | 0.73 | CA2 (0.32) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463470-A2 | Process for the preparation of a fluorotetrahydrofuranone derivative | F. HOFFMANN-LA ROCHE AG (CH) | 1992-01-02 | — | — | EP | claimed |
| EP-0463470-A2 | Process for the preparation of a fluorotetrahydrofuranone derivative | F. HOFFMANN-LA ROCHE AG (CH) | 1992-01-02 | — | — | EP | disclosed |