Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.54 |
| ▸ | CTSK | P43235 | 4/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652580 | 0.92 | PPARA (0.51) | CAPN1CTSKFOLH1SIRT2SIRT1 | |
| SCHEMBL19925534 | 0.87 | FOLH1 (0.64) | FOLH1SIRT2SIRT1MMEECE1 | |
| SCHEMBL19307785 | 0.87 | FOLH1 (0.64) | FOLH1SIRT2SIRT1MMEECE1 | |
| SCHEMBL9697060 | 0.87 | FOLH1 (0.64) | FOLH1SIRT2SIRT1MMEECE1 | |
| SCHEMBL9698236 | 0.87 | FOLH1 (0.64) | FOLH1SIRT2SIRT1MMEECE1 | |
| SCHEMBL24238520 | 0.87 | FOLH1 (0.64) | FOLH1SIRT2SIRT1MMEECE1 | |
| SCHEMBL10762779 | 0.87 | CTSK (0.50) | CAPN1CTSKFOLH1SIRT2SIRT1 | |
| SCHEMBL10541895 | 0.87 | CTSK (0.50) | CAPN1CTSKFOLH1SIRT2SIRT1 | |
| SCHEMBL9696050 | 0.86 | ALDH1A1 (0.58) | CTSKMMEECE1ALDH1A1ALOX15 | |
| SCHEMBL27626645 | 0.84 | FOLH1 (0.57) | CTSKFOLH1SIRT2SIRT1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509643-A1 | Anti-cancer compounds | BTG INTERNATIONAL LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |