Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3862544 | 0.87 | TSHR (0.49) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL17138161 | 0.85 | L3MBTL1 (0.65) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL2293325 | 0.84 | ATM (0.53) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL28755162 | 0.84 | ATM (0.53) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL28714996 | 0.84 | ATM (0.53) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL2287185 | 0.84 | ATM (0.53) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL2293709 | 0.82 | L3MBTL1 (0.54) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL8957417 | 0.79 | GAA (0.52) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL20519807 | 0.78 | PTGS2 (0.52) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL20520163 | 0.78 | PTGS2 (0.52) | GAAXBP1ATMNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093042-A | Site-specific for liver; diagnosis of metastatic cancer | THE UNIVERSITY OF MICHIGAN (US) | 1992-03-03 | — | — | US | disclosed |
| US-4957729-A | CONTRAST | THE UNIVERSITY OF MICHIGAN (US) | 1990-09-18 | — | — | US | disclosed |
| US-4873075-A | SITE-SPECIFIC TO LIVER AND HEPATOCYTE; SCINTIGRAPHY IMAGING | THE UNIVERSITY OF MICHIGAN (US) | 1989-10-10 | — | — | US | disclosed |