Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 5/20 | 0.33 |
| ▸ | F10 | P00742 | 5/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9594192 | 0.87 | MAPT (0.40) | MAPTRAB9APOLBTHRBBCHE | |
| SCHEMBL9198986 | 0.87 | GABBR2 (0.43) | GAATHRBKMT2A | |
| SCHEMBL9195308 | 0.77 | GAA (0.41) | GAATHRBALDH1A1KMT2AHPGD | |
| SCHEMBL9696447 | 0.76 | MAPT (0.40) | MAPTRAB9AGAA | |
| SCHEMBL9315021 | 0.74 | KDM4E (0.38) | MAPTRAB9AF2F10ALDH1A1 | |
| SCHEMBL9196668 | 0.72 | MAPT (0.44) | MAPTGAATHRBKMT2ASMN1; SMN2 | |
| SCHEMBL9203501 | 0.70 | GABBR2 (0.39) | GAATHRBKMT2A | |
| SCHEMBL9200322 | 0.70 | AKR1C3 (0.41) | MAPTGAAPOLBALDH1A1KMT2A | |
| SCHEMBL9315751 | 0.69 | GABBR2 (0.41) | GAATHRBKMT2A | |
| SCHEMBL9196657 | 0.69 | GABBR2 (0.41) | GAATHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162364-A | Treatment of spastic and senescence disorders | ADIR ET COMPAGNIE (FR) | 1992-11-10 | — | — | US | disclosed |