Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696413 | 0.87 | RAB9A (0.39) | MAPTRAB9AADAM17MAOAMAOB | |
| SCHEMBL9198993 | 0.86 | GABBR2 (0.44) | RAB9ALMNAGAAALOX5 | |
| SCHEMBL9696441 | 0.76 | MAPT (0.41) | MAPTRAB9AGAA | |
| SCHEMBL9195312 | 0.76 | GAA (0.43) | LMNAGAAALOX5 | |
| SCHEMBL9315029 | 0.73 | KDM4E (0.40) | MAPTLMNATP53MAOAMAOB | |
| SCHEMBL9196674 | 0.70 | MAOB (0.47) | TAS1R3TAS1R1ADAM17LMNAMAOB | |
| SCHEMBL12269180 | 0.70 | NPC1 (0.49) | MAPTRAB9ALMNATP53GAA | |
| SCHEMBL23731633 | 0.70 | MEN1 (0.45) | MAPTRAB9ALMNAGAAALOX5 | |
| SCHEMBL9315754 | 0.69 | PIM1 (0.55) | MAPTRAB9AADAM17LMNAMAOA | |
| SCHEMBL12869441 | 0.68 | PIM1 (0.58) | MAPTRAB9ALMNATP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162364-A | Treatment of spastic and senescence disorders | ADIR ET COMPAGNIE (FR) | 1992-11-10 | — | — | US | disclosed |