Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.64 |
| ▸ | PPARA | Q07869 | 17/20 | 0.64 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858489 | 0.91 | PPARG (0.76) | PPARGPPARA | |
| SCHEMBL10419456 | 0.87 | PPARA (0.73) | PPARGPPARA | |
| SCHEMBL9614051 | 0.85 | PPARA (0.67) | PPARGPPARA | |
| SCHEMBL9614120 | 0.84 | PPARA (0.66) | PPARGPPARA | |
| SCHEMBL9614013 | 0.84 | PPARA (0.66) | PPARGPPARA | |
| SCHEMBL9858575 | 0.81 | PPARA (0.63) | PPARGPPARA | |
| SCHEMBL9696806 | 0.81 | PPARA (0.63) | PPARGPPARA | |
| SCHEMBL1139006 | 0.80 | PPARG (0.50) | PPARGPPARAALDH1A1MAPT | |
| SCHEMBL10339334 | 0.79 | PPARG (0.67) | PPARGPPARA | |
| SCHEMBL6254262 | 0.78 | CTRC (0.54) | PPARGPPARAMMP2MMP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017435-A1 | OPTICALLY ACTIVE CARBOXYLIC ACIDS AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-15 | — | — | WO | disclosed |
| EP-0507238-A1 | Optically active carboxylic acids and medicinal preparations containing them | Roche Diagnostics GmbH (DE) | 1992-10-07 | — | — | EP | disclosed |