Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30556213 | 0.80 | CA1 (0.38) | CA12CA1CA9 | |
| SCHEMBL4787945 | 0.76 | CA12 (0.33) | CA12CA1CA9 | |
| SCHEMBL29787984 | 0.75 | HTT (0.35) | CA12CA1CA9 | |
| SCHEMBL24167590 | 0.73 | CA1 (0.54) | CA12CA1CA9 | |
| SCHEMBL30556207 | 0.73 | TSHR (0.44) | CA12CA1CA9 | |
| SCHEMBL2329763 | 0.73 | TSHR (0.44) | CA12CA1CA9 | |
| SCHEMBL1863318 | 0.73 | HTR7 (0.39) | CA12CA1CA9 | |
| SCHEMBL29497318 | 0.73 | HTR7 (0.39) | CA12CA1CA9 | |
| SCHEMBL2500390 | 0.72 | ALDH1A1 (0.39) | — | |
| SCHEMBL9562554 | 0.72 | HTR7 (0.38) | CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465802-A1 | Oxidant sensitive and insensitive aromatic esters as inhibitors of human neutrophil elastase | CORTECH, INC. (US) | 1992-01-15 | — | — | EP | disclosed |