Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27350234 | 0.78 | PDE9A (0.50) | PDE9AMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL28181864 | 0.76 | CHRNB2 (0.43) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL1252201 | 0.75 | PDE9A (0.45) | PDE9AALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL6403130 | 0.75 | AHR (0.50) | MEN1KMT2AALDH1A1HSD17B10MAPT | |
| SCHEMBL5808418 | 0.75 | MEN1 (0.42) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL29675282 | 0.74 | KDM4E (0.42) | PDE9AMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL2464667 | 0.73 | PDE9A (0.49) | PDE9AMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL29635217 | 0.73 | PDE9A (0.49) | PDE9AMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL28740845 | 0.73 | KDM4E (0.44) | PDE9AMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL28235853 | 0.72 | AHR (0.56) | MEN1KMT2AALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5090405-A | Polyether, siloxane, urethane block polymers | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| US-5047293-A | CONSISTING OF POLYISOCYANATE, CATALYST, AND CYCLOSILOXANE | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| US-4940047-A | POLYURETHANES, ORTHOPEDIC DRESSING | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-10 | — | — | US | disclosed |
| EP-0022634-A1 | Acylated indole derivatives, processes for their preparation and pharmaceutical compositions and drugs comprising them | TEIJIN LIMITED (JP) | 1981-01-21 | — | — | EP | disclosed |