Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | HRH1 | P35367 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15549479 | 0.89 | SIRT2 (0.68) | SIRT2SIRT1CYP3A4HTR6HRH1 | |
| SCHEMBL9615142 | 0.87 | SIRT2 (0.64) | SIRT2SIRT1CYP3A4HTR6HRH1 | |
| Hydrochloric Acid SCHEMBL9615130 | 0.86 | SIRT2 (0.62) | SIRT2SIRT1CYP3A4HTR6HRH1 | |
| SCHEMBL9615110 | 0.83 | NPC1 (0.54) | SIRT2SIRT1HTR6HRH1 | |
| Hydrochloric Acid SCHEMBL9615105 | 0.81 | KDM4E (0.53) | SIRT2SIRT1HTR6HRH1 | |
| SCHEMBL16602558 | 0.79 | HTR2A (0.50) | CYP3A4 | |
| SCHEMBL15536553 | 0.76 | HTR6 (0.69) | SIRT2SIRT1HTR6HRH1 | |
| SCHEMBL15550724 | 0.75 | SIRT2 (0.67) | SIRT2SIRT1CYP3A4 | |
| SCHEMBL9976718 | 0.72 | PSEN1 (0.53) | — | |
| Ammonia Solution, Strong SCHEMBL906134 | 0.72 | HTR6 (0.51) | HTR6HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169852-A | Anorexigenic agents | NEUREX CORPORATION (US) | 1992-12-08 | — | — | US | claimed |