Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | AGER | Q15109 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27357671 | 0.99 | KDM4E (0.49) | KDM4EALDH1A1SMN1; SMN2MAOBACHE | |
| SCHEMBL9370762 | 0.93 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2MAOBACHE | |
| Oxalic Acid SCHEMBL9368451 | 0.89 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2HRH3POLB | |
| Oxalic Acid SCHEMBL9697739 | 0.84 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2HRH3POLB | |
| SCHEMBL9532493 | 0.83 | MEN1 (0.54) | KDM4EMAOBACHEMAOAAGER | |
| SCHEMBL9527998 | 0.82 | MEN1 (0.51) | ALDH1A1MAOBACHEMAOAAGER | |
| Oxalic Acid SCHEMBL9531846 | 0.82 | HRH3 (0.64) | HRH3 | |
| Hydrochloric Acid SCHEMBL9527666 | 0.82 | KMT2A (0.53) | KDM4EMAOBACHEMAOAAGER | |
| SCHEMBL9699038 | 0.81 | MAOB (0.49) | ALDH1A1MAOBACHEMAOAHRH3 | |
| Hydrochloric Acid SCHEMBL9528708 | 0.81 | RAB9A (0.50) | ALDH1A1MAOBACHEMAOAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002501-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | disclosed |