Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267868 | 0.97 | PAM (0.45) | PAMMAPTLMNAMEN1MAPK1 | |
| Butadiene SCHEMBL1681602 | 0.94 | PAM (0.49) | PAMMAPTLMNAMEN1MAPK1 | |
| SCHEMBL2490104 | 0.91 | PAM (0.51) | PAMMAPTLMNAMEN1MAPK1 | |
| SCHEMBL9876554 | 0.89 | PAM (0.42) | PAMMAPTLMNAMEN1MAPK1 | |
| SCHEMBL208005 | 0.89 | PAM (0.46) | PAMMAPTLMNAMEN1MAPK1 | |
| SCHEMBL15194916 | 0.86 | MEN1 (0.42) | PAMMAPTLMNAMEN1MAPK1 | |
| SCHEMBL11819293 | 0.79 | PAM (0.40) | PAMMAPTLMNAMEN1MAPK1 | |
| SCHEMBL6977599 | 0.79 | MAPT (0.46) | PAMMAPTLMNAMEN1MAPK1 | |
| Styrene SCHEMBL3117319 | 0.79 | CYP3A4 (0.49) | MAPTLMNAMEN1MAPK1KMT2A | |
| SCHEMBL891181 | 0.78 | MMP1 (0.51) | PAMMAPTLMNAMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164434-A | Sulfide compound for thermal and/or oxidative stabilization of polymers | ROHM AND HAAS COMPANY (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0488550-A1 | Thermal stabilizers | ROHM AND HAAS COMPANY (US) | 1992-06-03 | — | — | EP | disclosed |