SCHEMBL9876554

SCHEMBL9876554

C=C(CC=Cc1ccccc1)C(=O)OC.C=CCOC(=O)C=C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAM P19021 1/20 0.42
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
LMNA P02545 3/20 0.41
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
MAOB P27338 2/20 0.40
CASP1 P29466 1/20 0.40
ALDH1A1 P00352 3/20 0.38
ALOX12 P18054 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP3A4 P08684 1/20 0.38
THRB P10828 1/20 0.37
MAOA P21397 1/20 0.37
APP P05067 1/20 0.36
NPC1 O15118 1/20 0.35
LIG1 P18858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7267868 0.91 PAM (0.45) PAMMEN1KMT2ALMNAKDM4E
Butadiene SCHEMBL9697334 0.89 PAM (0.43) PAMMEN1KMT2ALMNAKDM4E
Acrylic Acid Ethyl Ester SCHEMBL4746546 0.89 PAM (0.43) PAMMEN1KMT2ALMNAKDM4E
SCHEMBL208005 0.88 PAM (0.46) PAMMEN1KMT2ALMNAKDM4E
SCHEMBL96726 0.86 PAM (0.56) PAMMEN1KMT2ALMNAMAPT
SCHEMBL15194916 0.85 MEN1 (0.42) PAMMEN1KMT2ALMNAKDM4E
Acrylic Acid Ethyl Ester SCHEMBL8438535 0.85 RAB9A (0.40) PAMMEN1KMT2ALMNAKDM4E
SCHEMBL678004 0.85 TSHR (0.49) PAMMEN1KMT2AKDM4EMAOB
SCHEMBL2490104 0.85 PAM (0.51) PAMMEN1KMT2ALMNAKDM4E
Butadiene SCHEMBL337854 0.85 PAM (0.51) PAMMEN1KMT2ALMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5047480-A Acrylonitrile-methyl methacrylate-methylstyrene/A-/ terpolymer blend with maleic anhydride-stryene copolymer BAYER AKTIENGESELLSCHAFT (DE) 1991-09-10 US disclosed
EP-0057408-B1 PROCESS FOR PRODUCING GRAFT COPOLYMER KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-04-29 EP disclosed
US-4401806-A AFTER COAGULATION, IMPREGNATION WITH ORGANIC LIQUID, DISPERSION IN WATER, RECOVERING POWDER KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1983-08-30 US disclosed
EP-0057408-A2 Process for producing graft copolymer KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1982-08-11 EP disclosed