Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 8/20 | 0.61 |
| ▸ | LAP3 | P28838 | 5/20 | 0.61 |
| ▸ | GCLC | P48506 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 7/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605870 | 0.86 | FOLH1 (0.59) | ANPEPLAP3GCLC | |
| SCHEMBL9647092 | 0.86 | CA2 (0.55) | ANPEPLAP3GCLCSLC1A3SLC1A2 | |
| SCHEMBL9697359 | 0.84 | ANPEP (0.56) | ANPEPLAP3GCLCSLC1A3SLC1A2 | |
| SCHEMBL9646484 | 0.79 | ERAP1 (0.70) | ANPEPLAP3ERAP2ERAP1 | |
| SCHEMBL1304145 | 0.76 | FOLH1 (0.64) | GCLCSLC1A3SLC1A2SLC1A1CA2 | |
| SCHEMBL9645181 | 0.74 | LAP3 (0.57) | ANPEPLAP3SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL14927203 | 0.72 | GCLC (0.59) | GCLCSLC1A3SLC1A2SLC1A1CA2 | |
| SCHEMBL9647001 | 0.72 | LAP3 (0.72) | ANPEPLAP3SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9715079 | 0.72 | CHRM1 (0.52) | ANPEPLAP3GCLCSLC1A3SLC1A2 | |
| SCHEMBL2976105 | 0.72 | GCLC (0.48) | GCLCSLC1A3SLC1A2SLC1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147867-A | Bactericides, (carba)penicillins | MERCK & CO., INC. (US) | 1992-09-15 | — | — | US | claimed |
| EP-0366469-A2 | Phosphorus containing enzyme inhibitors | MERCK & CO. INC. (US) | 1990-05-02 | — | — | EP | claimed |
| US-5147867-A | Bactericides, (carba)penicillins | MERCK & CO., INC. (US) | 1992-09-15 | — | — | US | disclosed |
| US-5145990-A | Dehydropeptidase, carbapenicillin potentiation | MERCK & CO., INC. (US) | 1992-09-08 | — | — | US | disclosed |
| US-4962097-A | IN COMBINATION WITH A CARBAPENEM OR PENEM ANTIBIOTIC | MERCK & CO., INC. (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0366469-A2 | Phosphorus containing enzyme inhibitors | MERCK & CO. INC. (US) | 1990-05-02 | — | — | EP | disclosed |