Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9697236 | 0.98 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL4591978 | 0.80 | L3MBTL1 (0.34) | ALDH1A1L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL4592224 | 0.78 | L3MBTL1 (0.32) | ALDH1A1L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL7438590 | 0.72 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1MAPTPOLBLMNA | |
| SCHEMBL6248599 | 0.71 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL6632132 | 0.71 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL11469221 | 0.69 | CHRM2 (0.33) | — | |
| SCHEMBL27453240 | 0.69 | SIGMAR1 (0.43) | ALDH1A1L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL11446827 | 0.69 | SIGMAR1 (0.49) | ALDH1A1SIGMAR1KDM4E | |
| SCHEMBL4592349 | 0.69 | CHRM2 (0.37) | ALDH1A1MEN1KMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992003415-A1 | PROTEIN KINASE C MODULATORS | NOVA PHARMACEUTICAL CORPORATION (US) | 1992-03-05 | — | — | WO | disclosed |