Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699474 | 0.90 | NR1D1 (0.32) | FAAH | |
| SCHEMBL9385464 | 0.85 | PARP1 (0.34) | GPR119FAAH | |
| SCHEMBL9382016 | 0.85 | PARP1 (0.34) | GPR119FAAH | |
| SCHEMBL9382022 | 0.85 | PARP1 (0.34) | GPR119FAAH | |
| SCHEMBL9382090 | 0.83 | FAAH (0.32) | FAAH | |
| SCHEMBL9696886 | 0.82 | — | — | |
| SCHEMBL9194037 | 0.82 | GPR119 (0.30) | GPR119FAAH | |
| SCHEMBL9697625 | 0.81 | — | — | |
| SCHEMBL9697846 | 0.81 | — | — | |
| SCHEMBL9383362 | 0.81 | FAAH (0.31) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |