Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697942 | 0.78 | CHRM1 (0.45) | CHRM1CHRM2MEN1CYP2D6KMT2A | |
| SCHEMBL8935489 | 0.76 | CHRM2 (0.44) | CHRM1CHRM2MEN1CYP2D6KMT2A | |
| SCHEMBL25606145 | 0.75 | CHRM1 (0.40) | CHRM1CHRM2MEN1CYP2D6KMT2A | |
| SCHEMBL9696811 | 0.75 | CHRM1 (0.40) | CHRM1CHRM2MEN1CYP2D6KMT2A | |
| SCHEMBL21095754 | 0.73 | SLC6A12 (0.39) | CHRM1CHRM2MEN1CYP2D6KMT2A | |
| SCHEMBL21095889 | 0.73 | SLC6A12 (0.39) | CHRM1CHRM2MEN1CYP2D6KMT2A | |
| SCHEMBL9698974 | 0.72 | CHRNA7 (0.39) | CHRM1CHRM2MEN1CYP2D6KMT2A | |
| SCHEMBL15329099 | 0.71 | CHRM2 (0.43) | CHRM1CHRM2MEN1CYP2D6KMT2A | |
| SCHEMBL8935451 | 0.71 | CHRM2 (0.43) | CHRM1CHRM2MEN1CYP2D6KMT2A | |
| SCHEMBL18480318 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091397-A | Cognition activators | BEECHAM GROUP P.L.C. (GB) | 1992-02-25 | — | — | US | disclosed |
| EP-0363085-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-04-11 | — | — | EP | disclosed |