Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6017366 | 0.80 | ALDH1A1 (0.46) | MAPTKMT2ACYP2C19HIF1AALDH1A1 | |
| SCHEMBL27514567 | 0.77 | MAPT (0.42) | MAPTKMT2ACYP2C19HIF1AALDH1A1 | |
| SCHEMBL26105458 | 0.76 | ALDH1A1 (0.43) | MAPTKMT2ACYP2C19HIF1AALDH1A1 | |
| SCHEMBL200565 | 0.76 | ALDH1A1 (0.43) | MAPTKMT2ACYP2C19HIF1AALDH1A1 | |
| SCHEMBL27390196 | 0.76 | ALDH1A1 (0.43) | MAPTKMT2ACYP2C19HIF1AALDH1A1 | |
| SCHEMBL28606840 | 0.76 | ALDH1A1 (0.43) | MAPTKMT2ACYP2C19HIF1AALDH1A1 | |
| SCHEMBL10736177 | 0.76 | ALDH1A1 (0.43) | MAPTKMT2ACYP2C19HIF1AALDH1A1 | |
| SCHEMBL1615186 | 0.76 | CYP2C19 (0.43) | MAPTKMT2ACYP2C19HIF1AALDH1A1 | |
| SCHEMBL127044 | 0.76 | ALDH1A1 (0.43) | MAPTKMT2ACYP2C19HIF1AALDH1A1 | |
| SCHEMBL3995663 | 0.76 | ALDH1A1 (0.43) | MAPTKMT2ACYP2C19HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240010679-A1 | ANTINOCICEPTIVE COMPOUNDS AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2024-01-11 | — | — | US | claimed |
| WO-2022107049-A1 | ANTINOCICEPTIVE COMPOUNDS AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-05-27 | — | — | WO | claimed |
| EP-1511500-A4 | COMBINATION OF ANTI-MUSCARINIC AGENTS AND NON-GLUCOCORTICOID STEROIDS | EPIGENESIS PHARMACEUTICALS LLC (US) | 2009-04-29 | — | — | EP | claimed |
| JP-2006504666-A | — | — | 2006-02-09 | — | — | JP | claimed |
| CN-1674918-A | Compositions, formulations and kits for treating respiratory and pulmonary diseases using dehydroepiandrosterone steroids and antimuscarinic drugs | EPIGENESIS PHARMACEUTICALS INC (US) | 2005-09-28 | — | — | CN | claimed |
| EP-1511500-A2 | COMBINATION OF ANTI-MUSCARINIC AGENTS AND NON-GLUCOCORTICOID STEROIDS | Epigenesis Pharmaceuticals, Inc. (US) | 2005-03-09 | — | — | EP | claimed |
| WO-2004014293-A2 | COMBINATION OF ANTI-MUSCARINIC AGENTS AND NON-GLUCOCORTICOID STEROIDS | EPIGENESIS PHARMACEUTICALS, INC. (US) | 2004-02-19 | — | — | WO | claimed |
| US-20030216329-A1 | Composition, formulations & kit for treatment of respiratory & lung disease with dehydroepiandrosterone(s) steroid & an anti-muscarinic agent(s) | EPEGENESIS PHARMACEUTICALS, INC. | 2003-11-20 | — | — | US | claimed |
| US-6284750-B1 | DRUG, COSMETICS STEROID | ESTEE LAUDER INC. | 2001-09-04 | — | — | US | claimed |
| EP-0876391-B1 | NOVEL STEROID ESTERS USEFUL AGAINST SKIN DISORDERS | ESTEE LAUDER INC (US) | 2000-08-16 | — | — | EP | claimed |
| US-6025347-A | Steroid esters useful against skin disorders | ESTEE LAUDER INC. (US) | 2000-02-15 | — | — | US | claimed |
| US-5948418-A | MERCAPTANS | ESTEE LAUDER, INC. (US) | 1999-09-07 | — | — | US | claimed |
| US-5683705-A | Sulfur-based amides and bis-amides useful against skin disorders | ESTEE LAUDER, INC. (US) | 1997-11-04 | — | — | US | claimed |
| EP-0594656-A1 | 4-AMINO-3-HYDROXYCARBOXYLIC ACID DERIVATIVES | SANDOZ LTD. (CH) | 1994-05-04 | — | — | EP | claimed |
| WO-1993001166-A1 | 4-AMINO-3-HYDROXYCARBOXYLIC ACID DERIVATIVES | SANDOZ LTD. (CH) | 1993-01-21 | — | — | WO | claimed |
| US-20240010679-A1 | ANTINOCICEPTIVE COMPOUNDS AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2024-01-11 | — | — | US | disclosed |
| WO-2022107049-A1 | ANTINOCICEPTIVE COMPOUNDS AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-05-27 | — | — | WO | disclosed |
| EP-0594656-A1 | 4-AMINO-3-HYDROXYCARBOXYLIC ACID DERIVATIVES | SANDOZ LTD. (CH) | 1994-05-04 | — | — | EP | disclosed |
| EP-0542371-A1 | Saccharin derivative proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1993-05-19 | — | — | EP | disclosed |
| WO-1993001166-A1 | 4-AMINO-3-HYDROXYCARBOXYLIC ACID DERIVATIVES | SANDOZ LTD. (CH) | 1993-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216329-A1 | Composition, formulations & kit for treatment of respiratory & lung disease with dehydroepiandrosterone(s) steroid & an anti-muscarinic agent(s) | KIT, NR5A1, CHRM5 | MAPT 2996/4885KMT2A 1355/4885CYP2C19 944/4885 |
| US-20240010679-A1 | ANTINOCICEPTIVE COMPOUNDS AND USES THEREOF | OPRL1, OPRK1, OPRD1 | MAPT 1174/4885KMT2A 2212/4885CYP2C19 3098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.