Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | F13A1 | P00488 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | TGM1 | P22735 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL164180 | 0.90 | ALDH1A1 (0.51) | CCR6PAX8F13A1TGM2TGM1 | |
| SCHEMBL31629174 | 0.90 | CCR6 (0.62) | CCR6PAX8HTTHDAC1ALDH1A1 | |
| SCHEMBL7367495 | 0.87 | ALDH1A1 (0.58) | CCR6PAX8F13A1TGM2TGM1 | |
| SCHEMBL9699043 | 0.85 | CCR6 (0.59) | CCR6PAX8F13A1TGM2TGM1 | |
| SCHEMBL3968828 | 0.84 | CCR6 (0.54) | CCR6PAX8HTTALDH1A1ABCB1 | |
| SCHEMBL7366351 | 0.84 | CCR6 (0.53) | CCR6PAX8HTTALDH1A1MAPK1 | |
| SCHEMBL393422 | 0.84 | HTT (0.52) | CCR6PAX8F13A1TGM2TGM1 | |
| SCHEMBL2212416 | 0.84 | CCR6 (0.57) | CCR6PAX8HTTHDAC1ALDH1A1 | |
| SCHEMBL23683127 | 0.83 | CCR6 (0.56) | CCR6PAX8HTTHDAC1ALDH1A1 | |
| SCHEMBL389007 | 0.83 | HTT (0.51) | CCR6PAX8F13A1TGM2TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |