Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.59 |
| ▸ | F13A1 | P00488 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | TGM1 | P22735 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1897393 | 0.90 | CCR6 (0.51) | CCR6PAX8F13A1TGM2TGM1 | |
| SCHEMBL9698036 | 0.89 | CCR6 (0.59) | CCR6PAX8F13A1TGM2TGM1 | |
| SCHEMBL18057683 | 0.86 | CCR6 (0.61) | CCR6PAX8ALDH1A1MAPTHPGD | |
| SCHEMBL19346032 | 0.86 | CCR6 (0.53) | CCR6PAX8F13A1TGM2TGM1 | |
| SCHEMBL7367495 | 0.85 | ALDH1A1 (0.58) | CCR6PAX8F13A1TGM2TGM1 | |
| SCHEMBL29004736 | 0.85 | CCR6 (0.53) | CCR6PAX8F13A1TGM2TGM1 | |
| SCHEMBL9698980 | 0.85 | CCR6 (0.53) | CCR6PAX8F13A1TGM2TGM1 | |
| SCHEMBL3170360 | 0.85 | CCR6 (0.52) | CCR6PAX8F13A1TGM2TGM1 | |
| SCHEMBL8424282 | 0.85 | CCR6 (0.52) | CCR6PAX8F13A1TGM2TGM1 | |
| SCHEMBL553299 | 0.84 | ALDH1A1 (0.53) | CCR6PAX8F13A1TGM2TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |