Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 5/20 | 0.45 |
| ▸ | CNR2 | P34972 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9698600 | 1.00 | MEN1 (0.47) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL23851492 | 0.90 | GPR35 (0.49) | MEN1LMNAMAPTKMT2ACYP19A1 | |
| SCHEMBL16143752 | 0.84 | ALDH1A1 (0.51) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL3931562 | 0.83 | MEN1 (0.55) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL27765514 | 0.83 | GPR35 (0.51) | MEN1LMNAMAPTKMT2AGPR35 | |
| SCHEMBL9416503 | 0.82 | NPC1 (0.54) | MEN1LMNAMAPTKMT2ACYP19A1 | |
| Nitrophenolate SCHEMBL15923356 | 0.81 | NPC1 (0.60) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL28310966 | 0.81 | MAPT (0.48) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL5587927 | 0.78 | LMNA (0.53) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL10608059 | 0.78 | LMNA (0.53) | MEN1NR1I2LMNACHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147864-A | Bronchodilator agent, antianaphylactic agent, antishock agent, cardiotonic agent and anticarcinogenic agent | AMERICAN CYANAMID COMPANY (US) | 1992-09-15 | — | — | US | disclosed |
| US-4983592-A | Bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID CO. (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0374513-A2 | Novel bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |