Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 9/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9532042 | 0.99 | CCR2 (0.47) | CCR2KCNH2SIGMAR1KDM2BLTA4H | |
| SCHEMBL9699172 | 0.82 | CCR3 (0.43) | — | |
| Hydrochloric Acid SCHEMBL9527656 | 0.81 | CCR3 (0.42) | — | |
| Hydrochloric Acid SCHEMBL9527122 | 0.81 | SIGMAR1 (0.51) | CCR2KCNH2SIGMAR1KDM2B | |
| 1,2-Dichlorobenzene SCHEMBL27524525 | 0.79 | CARM1 (0.47) | KCNH2KDM2B | |
| SCHEMBL9696871 | 0.77 | KDM4E (0.50) | SIGMAR1KDM2B | |
| Hydrochloric Acid SCHEMBL27357671 | 0.76 | KDM4E (0.49) | SIGMAR1KDM2B | |
| SCHEMBL9368885 | 0.75 | SIGMAR1 (0.54) | KCNH2SIGMAR1 | |
| SCHEMBL1565984 | 0.74 | MEN1 (0.45) | CCR2KCNH2 | |
| Oxalic Acid SCHEMBL9697739 | 0.72 | KDM4E (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542844-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | claimed |
| WO-1992002501-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | claimed |