⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18776567 | 0.82 | TSHR (0.43) | — | |
| SCHEMBL12233187 | 0.81 | CHRNB2 (0.43) | — | |
| SCHEMBL12207092 | 0.81 | CTSK (0.46) | — | |
| SCHEMBL6934228 | 0.81 | — | — | |
| SCHEMBL104010 | 0.81 | ALOX15 (0.50) | — | |
| SCHEMBL5638554 | 0.81 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL11172899 | 0.81 | — | — | |
| SCHEMBL16512491 | 0.81 | — | — | |
| SCHEMBL22889048 | 0.80 | ALOX15 (0.43) | — | |
| SCHEMBL606445 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312200-B2 | 9-ketospinosyn derivatives | BAYER CROPSCIENCE AG (DE) | 2007-12-25 | — | — | US | claimed |
| US-20060128642-A1 | 9-Ketospinosyn derivatives | BAYER CROPSCIENCE AG (DE) | 2006-06-15 | — | — | US | claimed |
| US-11713335-B2 | Aminocoumarin compounds and methods of their use | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-08-01 | — | — | US | disclosed |
| US-11649214-B2 | Inhibitors of the notch transcriptional activation complex kinase (“NACK”) and methods for use of the same | UNIVERSITY OF MIAMI (US) | 2023-05-16 | — | — | US | disclosed |
| CN-111744678-B | Pretreatment method for deep sea sulfide flotation and ore dressing method for deep sea sulfide | 矿冶科技集团有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-111744678-A | Pretreatment method for deep sea sulfide flotation, beneficiation method for deep sea sulfide and deep sea sulfide flotation pretreatment agent | 矿冶科技集团有限公司 | 2020-10-09 | — | — | CN | disclosed |
| CN-107964011-A | Substituted pyrazolopyridines analog derivative and its medical usage | 中国人民解放军军事医学科学院毒物药物研究所 | 2018-04-27 | — | — | CN | disclosed |
| CN-107936039-A | Tricyclic condensed thiophene derivant as JAK inhibitor | 因赛特公司 | 2018-04-20 | — | — | CN | disclosed |
| US-20170216263-A1 | ARYL DIHYDROPYRIDINONES AND PIPERIDINONE MGAT2 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-08-03 | — | — | US | disclosed |
| WO-2017106134-A1 | BENZIMIDAZOLES AND INDOLES AS TARO INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-06-22 | — | — | WO | disclosed |
| US-9440958-B2 | Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases | INCYTE CORPORATION (US) | 2016-09-13 | — | — | US | disclosed |
| CN-1665811-A | Carbamate-substituted pyrazolopyridines | BAYER AG (DE) | 2005-09-07 | — | — | CN | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| US-5614519-A | (1-(2,3 or 4-N-morpholinoalkyl)-imidazol-4-yl)-benizimidazol-1-yl-methyl]-biphenyls useful as angiotensin-II antagonists | KARL THOMAE GMBH (DE) | 1997-03-25 | — | — | US | disclosed |
| US-5602127-A | ADMINISTERING TO TREAT HYPERTENSION | KARL THOMAE GMBH (DE) | 1997-02-11 | — | — | US | disclosed |
| US-5594003-A | HYPOTENSIVE AGENTS | DR. KARL THOMAE GMBH (DE) | 1997-01-14 | — | — | US | disclosed |
| US-5591762-A | HYPOTENSIVE AGENTS | DR. KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-4885286-A | LONG LASTING; CARBAMATE PHOSPHORYLATION | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1989-12-05 | — | — | US | disclosed |
| EP-0327663-A1 | Novel phosphonamidothionate derivatives and their use as pesticides | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1989-08-16 | — | — | EP | disclosed |
| US-4574159-A | Process for the preparation of O-methyl-N-vinylurethane | BAYER AKTIENGESELLSCHAFT (DE) | 1986-03-04 | — | — | US | disclosed |