Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | CTSE | P14091 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700554 | 0.86 | REN (0.55) | REN | |
| SCHEMBL9699211 | 0.80 | REN (0.59) | REN | |
| SCHEMBL9726166 | 0.80 | REN (0.44) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL9699556 | 0.79 | REN (0.57) | REN | |
| SCHEMBL9831906 | 0.78 | CTSS (0.43) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL9699193 | 0.77 | REN (0.58) | REN | |
| SCHEMBL9699228 | 0.74 | REN (0.51) | REN | |
| SCHEMBL9700854 | 0.74 | REN (0.55) | REN | |
| SCHEMBL9698173 | 0.74 | REN (0.54) | RENCTSDCTSE | |
| SCHEMBL7327167 | 0.73 | REN (0.50) | RENCTSDCTSECTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501280-A2 | Renin-inhibiting peptide analogues | MERCK PATENT GmbH (DE) | 1992-09-02 | — | — | EP | disclosed |