Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | CTSE | P14091 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831906 | 0.84 | CTSS (0.43) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL9726151 | 0.82 | REN (0.48) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL9264380 | 0.82 | REN (0.47) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL9270076 | 0.80 | REN (0.49) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL9270070 | 0.80 | REN (0.49) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL9699404 | 0.80 | REN (0.39) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL7326076 | 0.80 | REN (0.51) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL7281729 | 0.78 | REN (0.56) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL7290532 | 0.78 | REN (0.49) | REN | |
| SCHEMBL7334713 | 0.78 | CTSS (0.50) | RENCTSDCTSECTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147857-A | Enzyme inhibitors | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1992-09-15 | — | — | US | disclosed |
| EP-0446751-A1 | Glycolic acid derivatives | MERCK PATENT GmbH (DE) | 1991-09-18 | — | — | EP | disclosed |