Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propazine SCHEMBL9700542 | 0.90 | CYP3A4 (0.50) | LMNAHTTALDH1A1CYP3A4MAPT | |
| Propachlor SCHEMBL9525597 | 0.82 | ALDH1A1 (0.60) | LMNAHTTALDH1A1SMN1; SMN2TP53 | |
| Propachlor SCHEMBL7745776 | 0.82 | ALDH1A1 (0.60) | LMNAHTTALDH1A1SMN1; SMN2TP53 | |
| Propachlor SCHEMBL9711317 | 0.82 | ALDH1A1 (0.60) | LMNAHTTALDH1A1SMN1; SMN2TP53 | |
| Propachlor SCHEMBL28163636 | 0.82 | ALDH1A1 (0.60) | LMNAHTTALDH1A1SMN1; SMN2TP53 | |
| Propazine SCHEMBL9271309 | 0.78 | CYP3A4 (0.66) | ALDH1A1CYP3A4MAPTKMT2AMEN1 | |
| Propazine SCHEMBL9674230 | 0.78 | CYP3A4 (0.66) | ALDH1A1CYP3A4MAPTKMT2AMEN1 | |
| Propaquizafop SCHEMBL8984115 | 0.77 | ALDH1A1 (0.32) | LMNAHTTALDH1A1SMN1; SMN2TP53 | |
| Propazine SCHEMBL9219283 | 0.76 | HPGD (0.52) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| Propazine SCHEMBL10365903 | 0.76 | HPGD (0.52) | LMNASMN1; SMN2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004319-A1 | HERBICIDAL PYRROLESULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |