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Propachlor

Propachlor

SCHEMBL9711317

CC(C)N(C(=O)CCl)c1ccccc1.CC(C)N(C(=O)CCl)c1ccccc1.CCC(=O)Nc1ccc(Cl)c(Cl)c1.CCC(=O)Nc1ccc(Cl)c(Cl)c1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.60
▸ SMN1; SMN2 Q16637 4/20 0.60
▸ LMNA P02545 3/20 0.60
▸ CYP3A4 P08684 3/20 0.60
▸ TP53 P04637 2/20 0.60
▸ KMT2A Q03164 5/20 0.49
▸ MAPT P10636 5/20 0.49
▸ NPC1 O15118 3/20 0.49
▸ RAB9A P51151 3/20 0.49
▸ HTT P42858 2/20 0.49
▸ MEN1 O00255 4/20 0.48
▸ TSHR P16473 1/20 0.47
▸ ESRRA P11474 1/20 0.47
▸ POLB P06746 3/20 0.46
▸ CYP1A2 P05177 2/20 0.46
▸ CYP2D6 P10635 2/20 0.46
▸ CYP2C9 P11712 2/20 0.46
▸ CYP2C19 P33261 2/20 0.46
▸ NPSR1 Q6W5P4 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propachlor SCHEMBL9525597 1.00 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2LMNACYP3A4TP53
Propachlor SCHEMBL7745776 1.00 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2LMNACYP3A4TP53
Propachlor SCHEMBL28163636 1.00 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2LMNACYP3A4TP53
Propazine SCHEMBL9699546 0.82 LMNA (0.41) ALDH1A1SMN1; SMN2LMNACYP3A4TP53
Propachlor SCHEMBL9006379 0.80 ALDH1A1 (0.63) ALDH1A1SMN1; SMN2LMNACYP3A4TP53
Propanil SCHEMBL8936645 0.78 CYP3A4 (0.64) ALDH1A1LMNACYP3A4KMT2AMAPT
Propanil SCHEMBL26871 0.78 CYP3A4 (1.00) ALDH1A1SMN1; SMN2LMNACYP3A4KMT2A
Propanil SCHEMBL21900164 0.78 CYP3A4 (1.00) ALDH1A1SMN1; SMN2LMNACYP3A4KMT2A
Propanil SCHEMBL1702271 0.78 CYP3A4 (1.00) ALDH1A1SMN1; SMN2LMNACYP3A4KMT2A
Propachlor SCHEMBL65571 0.78 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2LMNATP53KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992020684-A1 HERBICIDAL OXATRICYCLIC ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-26 — — WO disclosed