Propachlor

Propachlor

SCHEMBL7745776

CC(C)N(C(=O)CCl)c1ccccc1.CCC(=O)Nc1ccc(Cl)c(Cl)c1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.60
SMN1; SMN2 Q16637 4/20 0.60
LMNA P02545 3/20 0.60
CYP3A4 P08684 3/20 0.60
TP53 P04637 2/20 0.60
KMT2A Q03164 5/20 0.49
MAPT P10636 5/20 0.49
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
HTT P42858 2/20 0.49
MEN1 O00255 4/20 0.48
TSHR P16473 1/20 0.47
ESRRA P11474 1/20 0.47
POLB P06746 3/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2D6 P10635 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
NPSR1 Q6W5P4 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propachlor SCHEMBL9525597 1.00 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2LMNACYP3A4TP53
Propachlor SCHEMBL9711317 1.00 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2LMNACYP3A4TP53
Propachlor SCHEMBL28163636 1.00 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2LMNACYP3A4TP53
Propazine SCHEMBL9699546 0.82 LMNA (0.41) ALDH1A1SMN1; SMN2LMNACYP3A4TP53
Propachlor SCHEMBL9006379 0.80 ALDH1A1 (0.63) ALDH1A1SMN1; SMN2LMNACYP3A4TP53
Propanil SCHEMBL8936645 0.78 CYP3A4 (0.64) ALDH1A1LMNACYP3A4KMT2AMAPT
Propanil SCHEMBL26871 0.78 CYP3A4 (1.00) ALDH1A1SMN1; SMN2LMNACYP3A4KMT2A
Propanil SCHEMBL21900164 0.78 CYP3A4 (1.00) ALDH1A1SMN1; SMN2LMNACYP3A4KMT2A
Propanil SCHEMBL1702271 0.78 CYP3A4 (1.00) ALDH1A1SMN1; SMN2LMNACYP3A4KMT2A
Propachlor SCHEMBL65571 0.78 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2LMNATP53KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210037817-A1 STABLE SOLID HERBICIDE DELIVERY SYSTEMS DOW AGROSCIENCES LLC (US) 2021-02-11 US disclosed
EP-1063883-A1 PESTICIDAL ADJUVANTS Dow Agrosciences LLC (US) 2001-01-03 EP disclosed
WO-1999048359-A1 PESTICIDAL ADJUVANTS DOW AGROSCIENCES LLC (US) 1999-09-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210037817-A1 STABLE SOLID HERBICIDE DELIVERY SYSTEMS SLC16A7, SLC16A3, DDT ALDH1A1 819/4885SMN1; SMN2 1352/4885LMNA 4677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.