Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15222202 | 0.83 | ALDH1A1 (0.54) | MAPTCYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL15442510 | 0.83 | TSHR (0.50) | MAPTTSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1903855 | 0.82 | GRIA1 (0.42) | MAPTCYP1A2 | |
| SCHEMBL30217885 | 0.82 | DTYMK (0.46) | MAPTTSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7325260 | 0.82 | HPGD (0.46) | HPGDMAPTTSHRCYP1A2CYP3A4 | |
| SCHEMBL4908896 | 0.82 | MAPT (0.46) | HPGDMAPTTSHR | |
| SCHEMBL7311809 | 0.81 | HPGD (0.56) | HPGDMAPTTSHRCYP1A2CYP3A4 | |
| SCHEMBL7474851 | 0.81 | MAPT (0.40) | MAPTCYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL971611 | 0.79 | MAPT (0.39) | MAPTCYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL1037500 | 0.78 | HTT (0.51) | MAPTCYP1A2CYP3A4CYP2D6CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171851-A | Cardiac stimulant | DONG-A PHARM. CO., LTD. (KR) | 1992-12-15 | — | — | US | disclosed |
| EP-0510235-A1 | Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same | DONG-A PHARM. CO., LTD. (KR) | 1992-10-28 | — | — | EP | disclosed |
| CN-85104392-A | The preparation method of quinolone inotropic agents | — | 1986-12-24 | — | — | CN | disclosed |