SCHEMBL9699643

SCHEMBL9699643

CC(C)C(C)(C)[Si](C)(C)OCCc1ccc(CCCBr)cc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9813441 0.91 MEN1 (0.38) MEN1KMT2A
SCHEMBL10633019 0.88 MEN1 (0.33) MEN1KMT2A
SCHEMBL9699540 0.85
SCHEMBL9699720 0.85 TAAR1 (0.36)
SCHEMBL9813460 0.82 CYP4F2 (0.40)
Bromide SCHEMBL9718283 0.80 IDO1 (0.37)
SCHEMBL9813440 0.80
SCHEMBL9813462 0.78 THRA (0.32)
SCHEMBL5871377 0.74 MEN1 (0.42) MEN1KMT2A
SCHEMBL9198674 0.74 TAAR1 (0.42) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5106991-A Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof E. R. SQUIBB & SONS, INC. (US) 1992-04-21 US disclosed
EP-0297768-B1 ARYLTHIOALKYLPHENYL CARBOXYLIC ACIDS, COMPOSITIONS CONTAINING SAME AND METHOD OF USE E.R. Squibb & Sons, Inc. (US) 1991-07-24 EP disclosed
EP-0400584-A2 Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof E.R. SQUIBB & SONS, INC. (US) 1990-12-05 EP disclosed
US-4975452-A Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof E. R. SQUIBB & SONS, INC. (US) 1990-12-04 US disclosed
EP-0297768-A1 Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use E.R. Squibb & Sons, Inc. (US) 1989-01-04 EP disclosed
US-4783473-A ANTICOAGULANTS, VASODILATORS, BRONCHODILATORS E. R. SQUIBB & SONS, INC. (US) 1988-11-08 US disclosed
US-4752616-A Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use E. R. SQUIBB & SONS, INC. (US) 1988-06-21 US disclosed