Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699643 | 0.91 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL9699720 | 0.88 | TAAR1 (0.36) | — | |
| SCHEMBL9813460 | 0.84 | CYP4F2 (0.40) | TDP1 | |
| SCHEMBL5871377 | 0.83 | MEN1 (0.42) | MEN1KMT2ATDP1 | |
| Bromide SCHEMBL9718283 | 0.83 | IDO1 (0.37) | — | |
| SCHEMBL9699540 | 0.82 | — | — | |
| SCHEMBL9768485 | 0.81 | MEN1 (0.38) | MEN1KMT2ATDP1 | |
| SCHEMBL10633019 | 0.79 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL9813438 | 0.77 | MEN1 (0.37) | MEN1KMT2ATDP1 | |
| SCHEMBL9198674 | 0.77 | TAAR1 (0.42) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297768-B1 | ARYLTHIOALKYLPHENYL CARBOXYLIC ACIDS, COMPOSITIONS CONTAINING SAME AND METHOD OF USE | E.R. Squibb & Sons, Inc. (US) | 1991-07-24 | — | — | EP | disclosed |
| EP-0297768-A1 | Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use | E.R. Squibb & Sons, Inc. (US) | 1989-01-04 | — | — | EP | disclosed |
| US-4752616-A | Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use | E. R. SQUIBB & SONS, INC. (US) | 1988-06-21 | — | — | US | disclosed |