Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538804 | 0.80 | HPGDS (0.42) | RIPK1MMP8SCN9AHPGDSHDAC3 | |
| SCHEMBL28170727 | 0.75 | ATG4B (0.47) | MMP8SCN9AHDAC3HDAC1HDAC2 | |
| SCHEMBL7662981 | 0.73 | EPHX2 (0.39) | RIPK1MMP8HPGDSHDAC3HDAC1 | |
| SCHEMBL19864372 | 0.73 | ATG4B (0.53) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL5720341 | 0.72 | CYP1A2 (0.48) | CFTRMGAM | |
| SCHEMBL8885055 | 0.72 | MGAM (0.44) | MMP8SCN9AHDAC3HDAC1HDAC2 | |
| SCHEMBL3638074 | 0.72 | KDM4A (0.52) | SCN9AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL9698478 | 0.71 | CCKBR (0.54) | MMP8MAPT | |
| SCHEMBL24392693 | 0.71 | HPGDS (0.70) | HPGDSHDAC3HDAC1HDAC2CFTR | |
| SCHEMBL11923151 | 0.70 | CYP1A2 (0.52) | MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004025-A1 | AMINO ACID ANALOGS AS CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | claimed |
| WO-1992004025-A1 | AMINO ACID ANALOGS AS CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |