Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699955 | 0.89 | TDP1 (0.51) | TDP1ALDH1A1HSD17B10APEX1RXRB | |
| SCHEMBL13945805 | 0.87 | CFTR (0.49) | TDP1ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL18542708 | 0.86 | GABRA1 (0.45) | TDP1ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL27960937 | 0.83 | TDP1 (0.42) | TDP1ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL4631399 | 0.82 | TDP1 (0.59) | TDP1ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL31350139 | 0.82 | TDP1 (0.50) | TDP1ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL28347865 | 0.82 | TDP1 (0.38) | TDP1ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL27888034 | 0.81 | TDP1 (0.57) | TDP1ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL27923138 | 0.81 | TDP1 (0.57) | TDP1ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL28393442 | 0.80 | TDP1 (0.37) | TDP1ALDH1A1HPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507576-A1 | Polypropylene-based resin compositions | TOSOH CORPORATION (JP) | 1992-10-07 | — | — | EP | disclosed |