Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699948 | 0.83 | TDP1 (0.42) | TDP1CES2APEX1CFTRALDH1A1 | |
| SCHEMBL13945805 | 0.81 | CFTR (0.49) | TDP1CFTRALDH1A1HPGDHSD17B10 | |
| SCHEMBL28347866 | 0.80 | TDP1 (0.36) | TDP1CES2APEX1ALDH1A1HPGD | |
| SCHEMBL18542708 | 0.80 | GABRA1 (0.45) | TDP1CES2APEX1ALDH1A1HPGD | |
| SCHEMBL28808753 | 0.78 | MAPT (0.41) | TDP1CFTRALDH1A1ALOX15HSD17B10 | |
| SCHEMBL27960891 | 0.78 | ALDH1A1 (0.46) | TDP1ALDH1A1HPGDLMNAGAA | |
| SCHEMBL31350139 | 0.77 | TDP1 (0.50) | TDP1CES2ALDH1A1HPGDALOX15 | |
| SCHEMBL4631399 | 0.77 | TDP1 (0.59) | TDP1ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL28347865 | 0.76 | TDP1 (0.38) | TDP1CES2APEX1ALDH1A1HPGD | |
| SCHEMBL29233049 | 0.76 | TDP1 (0.42) | TDP1CES2APEX1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103923072-A | Substituted Indazole Derivatives Active As Kinase Inhibitors | NERVIANO MEDICAL SCIENCES SRL | 2014-07-16 | — | — | CN | disclosed |
| CN-101754956-B | Substituted indazole derivatives active as kinase inhibitors | NERVIANO MEDICAL SCIENCES SRL | 2014-04-23 | — | — | CN | disclosed |