Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699251 | 0.86 | HPGD (0.54) | ALDH1A1LMNATHRBTP53MAPT | |
| SCHEMBL9682042 | 0.86 | PTGDR2 (0.53) | ALDH1A1ATMPTGDR2TBXA2R | |
| SCHEMBL9681428 | 0.85 | PTGDR2 (0.71) | PTGDR2TBXA2R | |
| SCHEMBL9581575 | 0.79 | TBXA2R (0.58) | PTGDR2TBXA2R | |
| SCHEMBL19851021 | 0.76 | TSHR (0.54) | ALDH1A1ATMPTGDR2KDM4ELMNA | |
| SCHEMBL9699174 | 0.76 | PTGDR2 (0.55) | ALDH1A1PTGDR2KDM4ELMNATBXA2R | |
| SCHEMBL9682472 | 0.76 | TBXA2R (0.57) | PTGDR2TBXA2R | |
| SCHEMBL10388365 | 0.75 | — | — | |
| SCHEMBL19851102 | 0.75 | TSHR (0.52) | ALDH1A1ATMPTGDR2KDM4ELMNA | |
| SCHEMBL9700273 | 0.74 | TBXA2R (0.77) | ALDH1A1ATMLMNATHRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |