SCHEMBL9700291

SCHEMBL9700291

Cc1cc(C=O)c(S(=O)(=O)F)cc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
ALDH1A1 P00352 5/20 0.35
TSHR P16473 3/20 0.35
ERN1 O75460 1/20 0.34
SMN1; SMN2 Q16637 5/20 0.34
GRIA1 P42261 1/20 0.33
GRIA2 P42262 1/20 0.33
GRIA3 P42263 1/20 0.33
GRIA4 P48058 1/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
GAA P10253 1/20 0.33
GFER P55789 1/20 0.33
MPI P34949 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9700422 0.79 GRIA1 (0.41) RAPGEF4CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL9698068 0.76 ALDH1A1 (0.33) ALDH1A1LMNA
SCHEMBL97117 0.74 GRIA1 (0.52) CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1
SCHEMBL30600409 0.74 ALDH1A1 (0.50) CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1
SCHEMBL446933 0.74 ALDH1A1 (0.50) CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1
SCHEMBL2884919 0.69 GRIA1 (0.56) CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1
SCHEMBL10018128 0.69 PRKDC (0.54) CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1
SCHEMBL12375394 0.69 ALDH1A1 (0.41) CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1
SCHEMBL7119052 0.68 GRIA1 (0.47) ALDH1A1TSHRERN1SMN1; SMN2GRIA1
SCHEMBL9699103 0.68 ALDH1A1 (0.42) CYP3A4CYP2C19ALDH1A1TSHRERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5095150-A FORMYLATED ALKLBENZENESULFONYL HALIDE COMPOUND AND PROCESS FOR PREPARING THE SAME AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1992-03-10 US disclosed
US-5030752-A Formylated alkylbenzenesulfonyl halide compound AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1991-07-09 US disclosed