Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.84 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | NPY1R | P25929 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | NPY2R | P49146 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.62 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20682737 | 0.91 | L3MBTL1 (1.00) | L3MBTL1MAPTNPY1RHTTNPY2R | |
| SCHEMBL15709049 | 0.91 | L3MBTL1 (1.00) | L3MBTL1MAPTNPY1RHTTNPY2R | |
| SCHEMBL13915620 | 0.82 | TDP1 (0.59) | L3MBTL1MAPTNPY1RHTTNPY2R | |
| SCHEMBL6776915 | 0.81 | L3MBTL1 (0.55) | L3MBTL1ABCB1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL20854834 | 0.80 | L3MBTL1 (0.77) | L3MBTL1MAPTNPY1RHTTNPY2R | |
| SCHEMBL1852361 | 0.79 | CYP2D6 (0.88) | L3MBTL1CYP1A2CYP2C19CYP2D6KMT2A | |
| SCHEMBL22640107 | 0.79 | LMNA (0.82) | L3MBTL1MAPTNPY1RNPY2RCYP1A2 | |
| SCHEMBL16370541 | 0.79 | LMNA (0.82) | L3MBTL1MAPTNPY1RNPY2RCYP1A2 | |
| SCHEMBL15296749 | 0.79 | ADRB2 (0.73) | L3MBTL1HTTCYP1A2CYP2C19ABCB1 | |
| SCHEMBL10769968 | 0.79 | ADRB2 (0.69) | L3MBTL1CYP1A2CYP2C19ABCB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112820-A | Vision defects | STERLING DRUG INC. (US) | 1992-05-12 | — | — | US | disclosed |
| US-5109135-A | 2- or 3-aminomethyl-4-amino-3,4-dihydro-2H-1,4-benzoxazine intermediates | STERLING DRUG INC. (US) | 1992-04-28 | — | — | US | disclosed |
| US-5066803-A | Chemical intermediates for analgesics | STERLING DRUG INC. (US) | 1991-11-19 | — | — | US | disclosed |
| WO-1990007505-A1 | 2- AND 3-AMINOMETHYL-6-ARYLCARBONYL-2,3-DIHYDROPYRROLO[1,2,3-de]-1,4-BENZOXAZINES | STERLING DRUG INC. (US) | 1990-07-12 | — | — | WO | disclosed |
| US-4939138-A | 2- and 3-aminomethyl-6-arylcarbonyl-2,3-dihydropyrrolo(1,2,3-DE)-1,4-benzoxazines | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |