Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25876517 | 0.85 | GSR (0.57) | GSRKMT2AMMP2MMP9MMP8 | |
| SCHEMBL2003577 | 0.83 | KMT2A (0.52) | KMT2A | |
| SCHEMBL461166 | 0.83 | GSR (0.65) | GSRKMT2AMMP2MMP9MMP8 | |
| SCHEMBL15556865 | 0.82 | GSR (0.59) | GSRMMP2MMP9MMP8PTGS2 | |
| SCHEMBL9701342 | 0.82 | GAA (0.46) | GSRAKR1C3 | |
| SCHEMBL10469774 | 0.82 | MEN1 (0.58) | KMT2APTGS2 | |
| SCHEMBL10541229 | 0.81 | GSR (0.54) | GSRKMT2AMMP2MMP9MMP8 | |
| Hydrochloric Acid SCHEMBL15465891 | 0.81 | GSR (0.60) | GSRMMP2MMP9MMP8PTGS2 | |
| SCHEMBL28296252 | 0.80 | GSR (0.53) | GSRKMT2AMMP2MMP9MMP8 | |
| SCHEMBL5058142 | 0.80 | GSR (0.61) | GSRMMP2MMP9MMP8PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112820-A | Vision defects | STERLING DRUG INC. (US) | 1992-05-12 | — | — | US | disclosed |
| US-5109135-A | 2- or 3-aminomethyl-4-amino-3,4-dihydro-2H-1,4-benzoxazine intermediates | STERLING DRUG INC. (US) | 1992-04-28 | — | — | US | disclosed |
| US-5066803-A | Chemical intermediates for analgesics | STERLING DRUG INC. (US) | 1991-11-19 | — | — | US | disclosed |
| WO-1990007505-A1 | 2- AND 3-AMINOMETHYL-6-ARYLCARBONYL-2,3-DIHYDROPYRROLO[1,2,3-de]-1,4-BENZOXAZINES | STERLING DRUG INC. (US) | 1990-07-12 | — | — | WO | disclosed |