Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700367 | 0.80 | GSR (0.57) | GSREPHX2NR1H4MMP2MMP9 | |
| SCHEMBL7444387 | 0.78 | RAB9A (0.55) | ALDH1A1PKMCA12CA1CA2 | |
| SCHEMBL7436867 | 0.78 | HSD17B3 (0.52) | NR1H4ALDH1A1CA12CA1CA2 | |
| SCHEMBL15464830 | 0.77 | EGLN1 (0.47) | GSREPHX2NR1H4ALDH1A1CA12 | |
| SCHEMBL3323642 | 0.77 | GSK3B (0.53) | ALDH1A1POLBMAPTRAB9AKMT2A | |
| SCHEMBL3786992 | 0.77 | GSK3B (0.53) | ALDH1A1POLBMAPTRAB9AKMT2A | |
| SCHEMBL25876517 | 0.77 | GSR (0.57) | GSREPHX2NR1H4MMP2MMP9 | |
| SCHEMBL7440297 | 0.77 | KMT2A (0.54) | ALDH1A1POLBMAPTRAB9AKMT2A | |
| SCHEMBL5058142 | 0.76 | GSR (0.61) | GSRMMP2MMP9MMP8PTGS2 | |
| SCHEMBL1185872 | 0.76 | GSR (0.61) | GSRMMP2MMP9MMP8PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109797174-B | Preparation method of florfenicol intermediate | 弈柯莱生物科技(上海)股份有限公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-109797174-A | A kind of preparation method of florfenicol midbody | 上海弈柯莱生物医药科技有限公司 | 2019-05-24 | — | — | CN | disclosed |