Dimethylamine

Dimethylamine

SCHEMBL9700399

CCCN(C)C(=O)C(=O)O.CNC

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.35
KDM5A P29375 4/20 0.33
KDM4C Q9H3R0 4/20 0.33
CA12 O43570 2/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
CA1 P00915 1/20 0.31
CA7 P43166 1/20 0.31
CA14 Q9ULX7 1/20 0.31
KDM5C P41229 1/20 0.30
KDM5B Q9UGL1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethylamine SCHEMBL9701283 0.87 EPHX2 (0.33) EPHX2KDM5AKDM4CCA12CA2
Dimethylamine SCHEMBL9702713 0.81 FFAR3 (0.30)
Dimethylamine SCHEMBL9701597 0.79
SCHEMBL42469 0.78
Hydrochloric Acid SCHEMBL10822824 0.75
SCHEMBL29736409 0.74 PRMT3 (0.36) KDM5AKDM4CCA12CA2CA9
SCHEMBL14098937 0.73 EPHX2 (0.38) EPHX2CA12CA2CA9TSHR
SCHEMBL9702710 0.73 CA12 (0.36) EPHX2KDM5AKDM4CCA12CA2
SCHEMBL9701553 0.73 MCHR1 (0.35) EPHX2ALOX15TSHRMAPK1
SCHEMBL209469 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5132454-A Antihypoxic agents MEIJI SEIKA KAISHA, LTD. (JP) 1992-07-21 US disclosed
EP-0387074-A2 Novel oxamic acid compounds and pharmaceutical composition for use in improvement of damaged cerebral functions of brain MEIJI SEIKA KAISHA LTD. (JP) 1990-09-12 EP disclosed