Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30888806 | 1.00 | KDM4E (0.50) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL30022590 | 0.98 | KDM4E (0.48) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL29986122 | 0.98 | KDM4E (0.48) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL1780998 | 0.85 | KDM4E (0.56) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL7879319 | 0.85 | KDM4E (0.49) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL29914907 | 0.85 | KDM4E (0.46) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL1356335 | 0.84 | KDM4E (0.50) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL29901541 | 0.84 | KDM4E (0.50) | KDM4ELMNACCR1CCR5CCR8 | |
| 2-Picolinic Acid SCHEMBL5670387 | 0.83 | LMNA (0.56) | KDM4ELMNAP4HTML3MBTL1NPC1 | |
| SCHEMBL3774471 | 0.81 | TGFBR1 (0.45) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118619998-A | Ir (C ' ≡ ') (C ' ≡N ') (C ' ++C ') ') configuration-based blue light tri-heteroleptic iridium (III) complex and preparation method thereof | 西北大学 | 2024-09-10 | — | — | CN | claimed |
| CN-118344407-A | Ir (C ' ≡ ') (C ' ≡N ') (N ' +O) -configuration-based blue light asymmetric tri-heteroleptic iridium (III) complex and preparation and application thereof | 西北大学 | 2024-07-16 | — | — | CN | claimed |
| EP-2350106-B1 | PHOSPHORESCENT IRIDIUM COMPLEXES | BOE TECHNOLOGY GROUP CO LTD (CN) | 2018-05-09 | — | — | EP | claimed |
| CN-102203109-B | Phosphorescent iridium complexes | GEN ELECTRIC | 2014-08-20 | — | — | CN | claimed |
| CN-101931054-B | White organic light emitting device | IND TECH RES INST | 2012-05-30 | — | — | CN | claimed |
| CN-102203109-A | Phosphorescent iridium complexes | GEN ELECTRIC | 2011-09-28 | — | — | CN | claimed |
| EP-2350106-A1 | PHOSPHORESCENT IRIDIUM COMPLEXES | General Electric Company (US) | 2011-08-03 | — | — | EP | claimed |
| US-7740956-B2 | Organic electroluminescent device | FUJIFILM CORPORATION (JP) | 2010-06-22 | — | — | US | claimed |
| WO-2010051100-A1 | PHOSPHORESCENT IRIDIUM COMPLEXES | GENERAL ELECTRIC COMPANY (US) | 2010-05-06 | — | — | WO | claimed |
| US-20100105852-A1 | PHOSPHORESCENT IRIDIUM COMPLEXES | GENERAL ELECTRIC COMPANY (US) | 2010-04-29 | — | — | US | claimed |
| EP-1086194-B1 | MONOSTABLE FERROELECTRIC ACTIVE MATRIX DISPLAY | AVENTIS RES & TECH GMBH & CO (DE) | 2003-05-21 | — | — | EP | claimed |
| US-6551668-B1 | Monodomain liquid crystal layer with an unambiguously defined direction of the layer normal z of the smectite phase wherein the layer normal z and the preferential direction n of the nematic or cholesteric phase (N* phase) form an angle of >/= 5 | AVENTIS RESEARCH & TECHNOLOGIES (DE) | 2003-04-22 | — | — | US | claimed |
| CN-118619998-A | Ir (C ' ≡ ') (C ' ≡N ') (C ' ++C ') ') configuration-based blue light tri-heteroleptic iridium (III) complex and preparation method thereof | 西北大学 | 2024-09-10 | — | — | CN | disclosed |
| CN-118344407-A | Ir (C ' ≡ ') (C ' ≡N ') (N ' +O) -configuration-based blue light asymmetric tri-heteroleptic iridium (III) complex and preparation and application thereof | 西北大学 | 2024-07-16 | — | — | CN | disclosed |
| CN-117940414-A | Compounds for targeting IRAK4 protein degradation | 渤健马萨诸塞州股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117447492-A | Polypyridine ligand for magnesium ion detection, iridium complex probe and preparation thereof | 南京邮电大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-1397559-A | Luminous organic intermetallic compound and luminous element | SANYO ELECTRIC CO (JP) | 2003-02-19 | — | — | CN | disclosed |
| US-6413448-B1 | ESTERS; DOPANTS; LONGER CHIRAL SMECTIC PHASE PITCH; HIGHER TILT ANGLE; LOWER VISCOSITY; CRYSTALLIZATION SUPPRESSION; IMPROVED SOLUBILITY; BROADER C* PHASE TEMPERATURE RANGE | DISPLAYTECH, INC. | 2002-07-02 | — | — | US | disclosed |
| WO-2000065801-A9 | CYCLOHEXYL- AND CYCLOHEXENYL-SUBSTITUTED LIQUID CRYSTALS WITH LOW BIREFRINGENCE | DISPLAYTECH INC (US) | 2001-04-12 | — | — | WO | disclosed |
| WO-2000065801-A1 | CYCLOHEXYL- AND CYCLOHEXENYL-SUBSTITUTED LIQUID CRYSTALS WITH LOW BIREFRINGENCE | DISPLAYTECH, INC. (US) | 2000-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105852-A1 | PHOSPHORESCENT IRIDIUM COMPLEXES | IGF1R, IRS1, IGF2R | KDM4E 4381/4885LMNA 4431/4885CCR1 427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.