SCHEMBL3774471

SCHEMBL3774471

Fc1cccc(-c2cccc(-c3ccccn3)c2)c1F.Fc1cccc(-c2cccc(-c3ccccn3)c2)c1F.Fc1cccc(-c2cccc(-c3ccccn3)c2)c1F.[Ir]

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.45
KAT6A Q92794 1/20 0.44
PDK2 Q15119 1/20 0.43
CYP2A6 P11509 1/20 0.41
GRM5 P41594 6/20 0.40
HTR1A P08908 1/20 0.40
HTR7 P34969 1/20 0.40
PRKDC P78527 1/20 0.40
KDM4E B2RXH2 3/20 0.40
MAPK1 P28482 2/20 0.40
TLR4 O00206 1/20 0.40
TLR2 O60603 1/20 0.40
ALDH1A1 P00352 1/20 0.40
RAB9A P51151 1/20 0.40
LMNA P02545 2/20 0.39
CCR1 P32246 2/20 0.39
CCR5 P51681 2/20 0.39
CCR8 P51685 2/20 0.39
CYP1A2 P05177 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3773646 0.90 TGFBR1 (0.50) TGFBR1KAT6APDK2CYP2A6GRM5
SCHEMBL2483821 0.89 TGFBR1 (0.51) TGFBR1KAT6APDK2CYP2A6GRM5
SCHEMBL17426491 0.83 KDM4E (0.52) TGFBR1PDK2CYP2A6GRM5HTR1A
SCHEMBL970044 0.81 KDM4E (0.50) TGFBR1GRM5HTR7KDM4EMAPK1
SCHEMBL30888806 0.81 KDM4E (0.50) TGFBR1GRM5HTR7KDM4EMAPK1
SCHEMBL3773686 0.80 GRM5 (0.47) TGFBR1KAT6APDK2CYP2A6GRM5
SCHEMBL3779014 0.80 GRM5 (0.59) TGFBR1KAT6APDK2CYP2A6GRM5
SCHEMBL30022590 0.80 KDM4E (0.48) TGFBR1GRM5HTR7KDM4EMAPK1
SCHEMBL29986122 0.80 KDM4E (0.48) TGFBR1GRM5HTR7KDM4EMAPK1
SCHEMBL502867 0.79 KDM4E (0.62) KAT6ACYP2A6GRM5HTR1AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1763902-B1 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2018-08-29 EP disclosed
US-8603645-B2 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORATION (US) 2013-12-10 US disclosed
US-8449990-B2 Electroluminescent efficiency UNIVERSAL DISPLAY CORPORATION (US) 2013-05-28 US disclosed
US-20110060143-A1 Stable and Efficient Electroluminescent Materials KWONG RAYMOND 2011-03-10 US disclosed
US-7851072-B2 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORATION (US) 2010-12-14 US disclosed
US-20070003789-A1 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORAITON 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110060143-A1 Stable and Efficient Electroluminescent Materials EML4, ITGA5, CHRM5 TGFBR1 2435/4885KAT6A 3480/4885PDK2 350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.