Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.52 |
| ▸ | PGK1 | P00558 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.41 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11487596 | 0.88 | NQO2 (0.46) | NQO2PGK1ALDH1A1PDGFRBPDGFRA | |
| SCHEMBL11477391 | 0.88 | NQO2 (0.46) | NQO2PGK1ALDH1A1PDGFRBPDGFRA | |
| SCHEMBL9701973 | 0.83 | NQO2 (0.39) | NQO2PGK1ALDH1A1KDM4EGLA | |
| SCHEMBL11696562 | 0.80 | PDE4A (0.54) | NQO2PGK1ALDH1A1PDGFRBPDGFRA | |
| SCHEMBL30932234 | 0.76 | ALDH1A1 (0.61) | NQO2ALDH1A1PDGFRBPDGFRASMN1; SMN2 | |
| SCHEMBL29600727 | 0.75 | ALDH1A1 (0.40) | NQO2PGK1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL571871 | 0.75 | ALDH1A1 (0.40) | NQO2PGK1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL1291852 | 0.75 | PGK1 (0.61) | NQO2PGK1ALDH1A1PDGFRBPDGFRA | |
| SCHEMBL4177978 | 0.75 | ERBB2 (0.61) | NQO2ALDH1A1PDGFRBSMN1; SMN2KDM4E | |
| SCHEMBL29029328 | 0.74 | NQO2 (0.62) | NQO2PGK1ALDH1A1PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014740-A1 | QUINOXALINE PHOSPHONO-AMINO ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-03 | — | — | WO | disclosed |
| US-5118675-A | Therapy for central nervous system disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |