Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699493 | 0.86 | SMN1; SMN2 (0.39) | ALDH3A1SMN1; SMN2TSHRALDH1A1HTT | |
| SCHEMBL4991751 | 0.76 | LMNA (0.45) | ALDH3A1SMN1; SMN2TSHRALDH1A1HTT | |
| SCHEMBL14263834 | 0.70 | TNF (0.57) | SMN1; SMN2TSHRALDH1A1HTTTP53 | |
| SCHEMBL7837246 | 0.70 | SMN1; SMN2 (0.56) | ALDH3A1SMN1; SMN2TSHRALDH1A1HTT | |
| SCHEMBL28063595 | 0.67 | SMN1; SMN2 (0.52) | ALDH3A1SMN1; SMN2TSHRALDH1A1HTT | |
| SCHEMBL21034360 | 0.67 | SMN1; SMN2 (0.52) | ALDH3A1SMN1; SMN2TSHRALDH1A1HTT | |
| SCHEMBL3490377 | 0.67 | SMN1; SMN2 (0.74) | ALDH3A1SMN1; SMN2TSHRALDH1A1HTT | |
| SCHEMBL8563059 | 0.66 | HPGD (0.42) | ALDH3A1TSHRALDH1A1HTTTP53 | |
| SCHEMBL9696683 | 0.62 | GRIN1 (0.37) | SMN1; SMN2ALDH1A1HTTMAPK1LMNA | |
| SCHEMBL22462449 | 0.61 | SMN1; SMN2 (0.66) | ALDH3A1SMN1; SMN2TSHRALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992001687-A1 | NOVEL OXAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-02-06 | — | — | WO | disclosed |