Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806521 | 0.85 | ALDH1A1 (0.48) | SMN1; SMN2MEN1KMT2APSMD14HPGD | |
| SCHEMBL9050387 | 0.84 | ALDH1A1 (0.47) | HPGDMAPTALDH1A1KDM4ECYP3A4 | |
| SCHEMBL29546973 | 0.83 | MAPK1 (0.60) | MEN1KMT2ATSHRMAPK1BACE1 | |
| SCHEMBL40312 | 0.83 | MAPK1 (0.60) | MEN1KMT2ATSHRMAPK1BACE1 | |
| Ethylene SCHEMBL8307653 | 0.81 | BACE1 (0.45) | SMN1; SMN2MEN1KMT2AHPGDMAPK1 | |
| 2-Nitrobenzaldehyde SCHEMBL9010354 | 0.81 | ERN1 (0.46) | SMN1; SMN2MEN1KMT2AHPGDMAPT | |
| SCHEMBL9052138 | 0.81 | ALDH1A1 (0.43) | HPGDMAPTALDH1A1KDM4ECYP3A4 | |
| SCHEMBL27623490 | 0.77 | MAPK1 (0.53) | TSHRMAPK1BACE1MAPTALDH1A1 | |
| 2-Nitrobenzaldehyde SCHEMBL10457932 | 0.74 | ERN1 (0.43) | SMN1; SMN2MEN1KMT2AHPGDMAPT | |
| SCHEMBL9699719 | 0.74 | ALDH1A1 (0.43) | MAPTALDH1A1KDM4ECYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171851-A | Cardiac stimulant | DONG-A PHARM. CO., LTD. (KR) | 1992-12-15 | — | — | US | disclosed |
| EP-0510235-A1 | Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same | DONG-A PHARM. CO., LTD. (KR) | 1992-10-28 | — | — | EP | disclosed |