SCHEMBL9050387

SCHEMBL9050387

CCOC(C)OCC.O=Cc1cc(Cl)c(Cl)cc1[N+](=O)[O-]

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
MAPT P10636 3/20 0.47
CYP3A4 P08684 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ALOX15 P16050 1/20 0.47
PRKDC P78527 1/20 0.47
HSD17B10 Q99714 1/20 0.47
VCAM1 P19320 5/20 0.38
KDM4A O75164 1/20 0.37
KDM4B O94953 1/20 0.37
ALDH3A1 P30838 2/20 0.36
FFAR1 O14842 1/20 0.35
LMNA P02545 2/20 0.35
HPGD P15428 2/20 0.34
GAA P10253 1/20 0.34
ERN1 O75460 1/20 0.33
PGK1 P00558 1/20 0.33
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9052138 0.91 ALDH1A1 (0.43) ALDH1A1MAPTCYP3A4KDM4EALOX15
SCHEMBL9700757 0.84 SMN1; SMN2 (0.45) ALDH1A1MAPTCYP3A4KDM4EALOX15
SCHEMBL4988910 0.82 HSD17B10 (0.55) ALDH1A1MAPTCYP3A4KDM4EALOX15
2-Nitrobenzaldehyde SCHEMBL9010354 0.77 ERN1 (0.46) ALDH1A1MAPTKDM4ELMNAHPGD
Ethylene SCHEMBL8307653 0.76 BACE1 (0.45) ALDH1A1MAPTCYP3A4KDM4EALOX15
SCHEMBL5583374 0.73 VCAM1 (0.55) ALDH1A1MAPTCYP3A4KDM4EALOX15
SCHEMBL6918730 0.73 LMNA (0.40) ALDH1A1LMNAHPGDGAAERN1
SCHEMBL8807505 0.72 MAPT (0.53) ALDH1A1MAPTCYP3A4KDM4EALOX15
SCHEMBL13527036 0.72 HSD17B10 (0.53) ALDH1A1MAPTCYP3A4KDM4EALOX15
SCHEMBL10478087 0.72 ALDH1A1 (0.43) ALDH1A1MAPTCYP3A4KDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8268974-A None JP disclosed
JP-H08268974-A 3-FLUORO-4-CHLORO-6-NITROBENZALDEHYDE, 3-FLUORO-4-CHLORO-6-NITROBENZALDEHYDE ACETAL AND THEIR PRODUCTION UBE IND LTD 1996-10-15 JP disclosed