Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4573202 | 0.86 | MAPK1 (0.44) | TSHRMAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL2928829 | 0.83 | MAPK1 (0.53) | TSHRMAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL4715558 | 0.78 | ALDH1A1 (0.50) | TSHRMAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL13176425 | 0.78 | MAPK1 (0.47) | TSHRMAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL10478039 | 0.78 | ALDH1A1 (0.51) | TSHRMAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL13875029 | 0.77 | MAPK1 (0.58) | TSHRMAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL316689 | 0.76 | MAPT (0.57) | TSHRMAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL11490458 | 0.76 | VCAM1 (0.42) | TSHRMAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL10648437 | 0.75 | MEN1 (0.42) | TSHRMAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL31198103 | 0.75 | MEN1 (0.45) | TSHRMAPK1MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171851-A | Cardiac stimulant | DONG-A PHARM. CO., LTD. (KR) | 1992-12-15 | — | — | US | disclosed |
| EP-0510235-A1 | Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same | DONG-A PHARM. CO., LTD. (KR) | 1992-10-28 | — | — | EP | disclosed |
| US-4415572-A | CARDIOTONIC AND INOTROPIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |