Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11484535 | 0.77 | TDP1 (0.56) | VCAM1ALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL17323178 | 0.77 | MEN1 (0.43) | ALDH1A1TSHRTDP1CYP3A4FFAR1 | |
| SCHEMBL28115557 | 0.76 | ALDH1A1 (0.47) | VCAM1ALDH1A1TDP1HIF1AFFAR1 | |
| SCHEMBL9700761 | 0.76 | TSHR (0.49) | VCAM1ALDH1A1TSHRHPGDTDP1 | |
| SCHEMBL11495006 | 0.76 | ALDH1A1 (0.49) | ALDH1A1HPGDCYP3A4LMNAMAPT | |
| SCHEMBL10976006 | 0.76 | VCAM1 (0.44) | VCAM1ALDH1A1TSHRHPGDTDP1 | |
| SCHEMBL10797402 | 0.74 | TSHR (0.50) | VCAM1ALDH1A1TSHRHPGDTDP1 | |
| SCHEMBL10478039 | 0.71 | ALDH1A1 (0.51) | ALDH1A1TSHRTDP1LMNAMAPT | |
| SCHEMBL11515841 | 0.71 | VCAM1 (0.50) | VCAM1ALDH1A1TSHRHPGDTDP1 | |
| SCHEMBL11692703 | 0.70 | ALDH1A1 (0.47) | ALDH1A1TSHRTDP1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4192670-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1980-03-11 | — | — | US | disclosed |
| US-4054439-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1977-10-18 | — | — | US | disclosed |