Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005993 | 0.73 | KDM4E (0.42) | HDAC6L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL9005973 | 0.73 | BCAT2 (0.38) | HDAC6L3MBTL1ALDH1A1POLBHTT | |
| SCHEMBL7650615 | 0.71 | HDAC6 (0.62) | HDAC6L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL7450221 | 0.70 | HDAC6 (0.65) | HDAC6L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL1430605 | 0.69 | FFAR1 (0.49) | KEAP1FFAR1AKR1B1 | |
| SCHEMBL3926861 | 0.69 | FFAR1 (0.49) | KEAP1FFAR1AKR1B1 | |
| SCHEMBL9701710 | 0.68 | NPSR1 (0.38) | HDAC6POLBFFAR1 | |
| SCHEMBL233492 | 0.67 | HPGD (0.50) | HPGD | |
| SCHEMBL28455008 | 0.67 | HDAC6 (0.68) | HDAC6L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL28449800 | 0.65 | HDAC6 (0.64) | HDAC6L3MBTL1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014740-A1 | QUINOXALINE PHOSPHONO-AMINO ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-03 | — | — | WO | claimed |