SCHEMBL9701710

SCHEMBL9701710

NOP(=O)(O)Cc1cc2nccnc2cc1CCC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.38
FFAR1 O14842 2/20 0.34
PLAU P00749 1/20 0.33
POLB P06746 1/20 0.31
GRIA2 P42262 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
FOS P01100 1/20 0.30
JUN P05412 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9701703 0.71 PLAU (0.34) PLAU
SCHEMBL9005973 0.70 BCAT2 (0.38) NPSR1POLBHDAC6
SCHEMBL9005993 0.69 KDM4E (0.42) HDAC6
SCHEMBL9700764 0.68 HDAC6 (0.53) FFAR1POLBHDAC6
SCHEMBL9701718 0.66 PGK1 (0.39)
SCHEMBL1430605 0.64 FFAR1 (0.49) FFAR1
SCHEMBL3926861 0.64 FFAR1 (0.49) FFAR1
SCHEMBL367757 0.61 GRM8 (0.42)
SCHEMBL234493 0.60 LMNA (0.43) NPSR1HDAC6
SCHEMBL453385 0.58 LMNA (0.48) NPSR1FFAR1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992014740-A1 QUINOXALINE PHOSPHONO-AMINO ACIDS AMERICAN HOME PRODUCTS CORPORATION (US) 1992-09-03 WO disclosed