Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005993 | 0.82 | KDM4E (0.42) | HDAC6L3MBTL1ALDH1A1 | |
| SCHEMBL8645093 | 0.78 | PRKAG1 (0.37) | NPSR1 | |
| SCHEMBL9700764 | 0.73 | HDAC6 (0.53) | HDAC6L3MBTL1POLBHTTALDH1A1 | |
| SCHEMBL9701710 | 0.70 | NPSR1 (0.38) | HDAC6NPSR1POLB | |
| SCHEMBL8644134 | 0.69 | — | — | |
| SCHEMBL9005979 | 0.68 | KDM4E (0.36) | HDAC6L3MBTL1NPSR1 | |
| SCHEMBL6666177 | 0.62 | EGFR (0.49) | ALDH1A1MAPT | |
| SCHEMBL3926861 | 0.59 | FFAR1 (0.49) | — | |
| SCHEMBL1430605 | 0.59 | FFAR1 (0.49) | — | |
| SCHEMBL8708279 | 0.59 | TBXA2R (0.54) | HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736032-A1 | HETEROCYCLIC COMPOUNDS | Astra Aktiebolag (SE) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017410-A1 | HETEROCYCLIC COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1995-06-29 | — | — | WO | disclosed |